Identifying the associations between head impact biomechanics and clinical recovery may inform better head impact monitoring procedures and identify athletes who may benefit from early treatments aimed to enhance recovery. The purpose of this study was to test whether head injury biomechanics are associated with clinical recovery of symptom severity, balance, and mental status, as well as symptom resolution time (SRT) and return-to-participation (RTP) time. We studied 45 college American football players (n = 51 concussions) who sustained an incident concussion while participating in a multi-site study. Player race/ethnicity, prior concussion, medical history, position, body mass index, event type, and impact location were covariates in our multivariable analyses. Multivariable negative binomial regression models analyzed associations between our study outcomes and (1) injury-causing linear and rotational head impact severity, (2) season repetitive head impact exposure (RHIE), and (3) injury day RHIE. Median SRT was 6.1 days (IQR 5.8 days, n = 45) and median RTP time was 12.3 days (IQR 7.8 days, n = 36) across our study sample. RTP time was 86% (Ratio 1.86, 95% CI [1.05, 3.28]) longer in athletes with a concussion history. Offensive players had SRTs 49% shorter than defensive players (Ratio 0.51, 95% CI [0.29, 0.92]). Per-unit increases in season RHIE were associated with 22% longer SRT (Ratio 1.22, 95% CI [1.09, 1.36]) but 28% shorter RTP time (Ratio 0.72, 95% CI [0.56, 0.93]). No other head injury biomechanics predicted injury recovery.

确定头部撞击生物力学与临床恢复之间的关联可以为更好的头部撞击监测程序提供信息，并确定可能从旨在促进恢复的早期治疗中受益的运动员。本研究的目的是测试头部损伤生物力学是否与症状严重程度、平衡和精神状态的临床恢复以及症状缓解时间 (SRT) 和恢复参与 (RTP) 时间有关。我们研究了 45 名美国大学橄榄球运动员 ( n = 51 次脑震荡）在参与多站点研究时发生脑震荡。球员种族/民族、既往脑震荡、病史、位置、体重指数、事件类型和撞击位置是我们多变量分析中的协变量。多变量负二项回归模型分析了我们的研究结果与 (1) 致伤线性和旋转头部撞击严重程度、(2) 季节重复性头部撞击暴露 (RHIE) 和 (3) 受伤日 RHIE 之间的关联。中位 SRT 为 6.1 天（IQR 5.8 天，n  = 45），中位 RTP 时间为 12.3 天（IQR 7.8 天，n = 36) 在我们的研究样本中。有脑震荡史的运动员的 RTP 时间长 86%（Ratio 1.86, 95% CI [1.05, 3.28]）。进攻球员的 SRT 比防守球员短 49%（Ratio 0.51, 95% CI [0.29, 0.92]）。RHIE 季节每单位增加与 SRT 延长 22%（Ratio 1.22, 95% CI [1.09, 1.36]）有关，但 RTP 时间缩短 28%（Ratio 0.72, 95% CI [0.56, 0.93]）。没有其他头部损伤生物力学预测损伤恢复。