当前位置: X-MOL 学术Nano Express › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Assessment of antibacterial and anticancer capability of silver nanoparticles extracellularly biosynthesized using Aspergillus terreus
Nano Express ( IF 2.7 ) Pub Date : 2020-10-30 , DOI: 10.1088/2632-959x/abc2e4
R Mankamna Kumari 1 , Vikram Kumar 2 , Manish Kumar 2 , Nidhi Pareek 2 , Surendra Nimesh 1
Affiliation  

The present study explores biosynthesis of silver nanoparticles (AgNPs) employing extracellular extract of Aspergillus terreus ITCC 9932.15. Modulation of various variables that dictate the biosynthesis of AgNPs, suggested of optimal AgNPs synthesis using AgNO 3 , 1 mM at pH 8 and temperature, 35 °C. The biosynthesis of AgNPs was observed to be time dependent with incremental particle synthesis till 24 h. Various studies were undertaken to authenticate formation and characterization of AgNPs for size, crystallinity and biomolecules involved. A sharp SPR peak observed at 420 nm in the UV–vis absorption spectra validated synthesis of nanoparticles. These particles exhibited spherical morphology with size ∼25 nm and −16 mV of zeta potential. Further, the existence of proteins and other biomolecules onto the surface of AgNPs was confirmed with FTIR studies. The SAED pattern investigated by employing TEM authenticated the crystallinity of AgNPs. The AgNPs also exhibit...

中文翻译:

评估曲霉曲霉在细胞外生物合成的银纳米颗粒的抗菌和抗癌能力

本研究探索了利用银曲霉菌ITCC 9932.15的细胞外提取物来银纳米颗粒(AgNPs)的生物合成。调节指示AgNPs生物合成的各种变量的建议,建议使用AgNO 3(pH 1为8 mM,pH 8和温度为35°C)最佳合成AgNPs。观察到AgNPs的生物合成是时间依赖性的,直到24 h为止颗粒的合成不断增加。进行了各种研究以鉴定涉及大小,结晶度和生物分子的AgNP的形成和表征。在紫外可见吸收光谱中在420 nm处观察到一个尖锐的SPR峰,验证了纳米颗粒的合成。这些颗粒呈现出球形形态,尺寸约为25 nm,ζ电位为-16 mV。进一步,FTIR研究证实了AgNPs表面蛋白质和其他生物分子的存在。通过TEM研究的SAED模式验证了AgNPs的结晶度。AgNP也表现出...
更新日期:2020-10-30
down
wechat
bug