Objective . Direct electrical stimulation of the brain through intracranial electrodes is currently used to probe the epileptic brain as part of pre-surgical evaluation, and it is also being considered for therapeutic treatments through neuromodulation. In order to effectively modulate neural activity, a given neuromodulation design must elicit similar responses throughout the course of treatment. However, it is unknown whether intracranial electrical stimulation responses are consistent across sessions. The objective of this study was to investigate the within-subject, cross-session consistency of the electrophysiological effect of electrical stimulation delivered through intracranial electroencephalography (iEEG). Approach . We analysed data from 79 epilepsy patients implanted with iEEG who underwent brain stimulation as part of a memory experiment. We quantified the effect of stimulation in terms of band power modulation and compared this effect from session to s...

中文翻译：

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通过颅内 EEG 刺激进行频带功率调制及其跨会话一致性

客观的 。作为术前评估的一部分，目前通过颅内电极对大脑进行直接电刺激用于探测癫痫大脑，并且也正在考虑通过神经调节进行治疗。为了有效调节神经活动，给定的神经调节设计必须在整个治疗过程中引发类似的反应。然而，目前尚不清楚颅内电刺激反应是否在各个会话中保持一致。本研究的目的是调查通过颅内脑电图 (iEEG) 传递的电刺激的电生理效应的受试者内、跨会话一致性。方法 。我们分析了 79 名植入 iEEG 的癫痫患者的数据，这些患者在记忆实验中接受了脑刺激。我们根据频带功率调制量化了刺激的效果，并将这种效果从会话到 s...