We introduce a method of azimuthally invariant 3D Mueller-matrix (MM) layer-by-layer mapping of the phase and amplitude parameters of anisotropy of the partially depolarizing layers of benign (adenoma) and malignant (carcinoma) prostate tumours. The technique is based on the analysis of spatial variations of Mueller matrix invariant (MMI) of histological sections of benign (adenoma) and malignant (carcinoma) tissue samples. The phase dependence of magnitudes of the first-to-fourth order statistical moments is applied to characterize 3D spatial distributions of MMI of linear and circular birefringence and dichroism of prostate tumours. The high order statistical moments and phase sections of the optimal differentiation of the polycrystalline structure of tissue samples are revealed. The obtained results are compared with the results obtained by conventional methods utilizing polarized light, including 2D and 3D Mueller matrix imaging.

中文翻译：

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基于3D Mueller矩阵的良性和恶性软组织肿瘤内多晶结构的方位不变层析成像

我们介绍了一种方法，对良性（腺瘤）和恶性（癌）前列腺肿瘤的部分去极化层的各向异性的相位和幅度参数进行逐层不变的3D Mueller-matrix（MM）逐层映射。该技术基于对良性（腺瘤）和恶性（癌）组织样本的组织切片的穆勒矩阵不变性（MMI）的空间变化进行分析。一阶至四阶统计矩的幅度的相位相关性用于表征线性和圆形双折射MMI的3D空间分布以及前列腺肿瘤的二向色性。揭示了组织样品的多晶结构的最佳分化的高阶统计矩和相位截面。