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Treatment with Ceftriaxone in Complicated Diverticulitis Increases the Incidence of Intra-Abdominal Enterococcus faecium Detection
Surgical Infections ( IF 1.4 ) Pub Date : 2021-05-18 , DOI: 10.1089/sur.2020.057
Julius Pochhammer 1, 2 , Axel Kramer 3 , Matthias Orth 4 , Michael Schäffer 2 , Jan Henrik Beckmann 1
Affiliation  

Background: Complicated diverticulitis of the sigmoid colon typically is treated by resection after initial antibiotic treatment. Third-generation cephalosporins are the drugs of choice but are not effective against enterococci and can induce colonic colonization by Enterococcus faecium within hours. Infections caused by enterococci, especially E. faecium, are difficult to treat but should be considered in the strategic treatment planning of hospital-acquired peritonitis (e.g., anastomotic leakage), especially in immunocompromised patients.

中文翻译:

头孢曲松治疗复杂性憩室炎会增加腹内屎肠球菌检测的发生率

背景:乙状结肠的复杂憩室炎通常在初始抗生素治疗后切除。第三代头孢菌素是首选药物,但对肠球菌无效,可在数小时内诱导粪肠球菌在结肠定植。肠球菌,尤其是粪肠球菌引起的感染难以治疗,但应在医院获得性腹膜炎(如吻合口漏)的战略治疗计划中予以考虑,尤其是在免疫功能低下的患者中。
更新日期:2021-06-03
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