Background: Colistin resistance in Acinetobacter baumannii, the last resort drug for serious infections, is emerging worldwide. There has been paucity of data on this aspect from India, which is one of the largest producers of colistin. We studied colistin resistance in A. baumannii and characterized the isolates with respect to resistance mechanisms and virulence.

中文翻译：

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来自印度三级医院的耐粘菌素鲍曼不动杆菌的 pmrA/B 和 lpxA/D 基因新位点突变和适应性降低

背景：鲍曼不动杆菌的粘菌素耐药性是治疗严重感染的最后手段，在世界范围内正在出现。印度缺乏这方面的数据，印度是粘菌素的最大生产国之一。我们研究了鲍曼不动杆菌的粘菌素抗性，并在抗性机制和毒力方面对分离株进行了表征。