Objectives Neuromyelitis optica is a devastating, relapsing, inflammatory, autoimmune disorder characterised in large part by attacks of optic neuritis and transverse myelitis causing blindness and plegia in many patients. Eighty-three per cent of patients with transverse myelitic attacks and 67% of patients with optic neuritis attacks have no or a partial recovery. Methods Results from The European Group for Blood and Marrow Transplantation Autoimmune Diseases Working Party imply failure of autologous haematopoietic stem cell bone marrow transplantation. Results and conclusion We present a case that despite eventual relapse, made a remarkable functional recovery after bone marrow transplantation which may justify bone marrow transplantation in severe cases.

中文翻译：

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行走瘫痪：严重 NMOSD 复发的 AHSCBMT

目的 视神经脊髓炎是一种破坏性、复发性、炎症性、自身免疫性疾病，其主要特征是视神经炎和横贯性脊髓炎的发作，导致许多患者失明和瘫痪。83% 的横贯性脊髓炎患者和 67% 的视神经炎患者没有或部分康复。方法 欧洲血液和骨髓移植组织自身免疫性疾病工作组的结果表明自体造血干细胞骨髓移植失败。结果和结论 我们提出了一个病例，尽管最终复发，但在骨髓移植后取得了显着的功能恢复，这可能证明在严重病例中进行骨髓移植是合理的。