The noble metal-based nanoparticles (NPs) have been considered as potential antimicrobial agents because of their good antibacterial and antifungal activities as well as biocompatible nature. In this study, we have introduced a simple and fast route to synthesize silver, gold, and silver-gold bimetallic NP-decorated dextran. The as-synthesized noble metal-based NPs with spherical geometry showed high dispersity in dextran. The antibacterial and antifungal of obtained nanomaterials were tested with Xanthomonas oryzae pv. oryzae (Xoo) bacteria and Magnaporthe grisea (M. grisea) fungi. The silver NPs and bimetallic NPs with high silver content in dextran exhibited excellent activity to inhibited the growth of the bacteria and fungi, whereas the gold/dextran has weak antimicrobial effects. The antibacterial and antifungal properties of silver-gold bimetallic NPs in dextran biopolymer can be tuned according to the content of silver in the bimetallic NPs. The obtained nanomaterials could open an entry to a new class of antibiotics.

中文翻译：

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银，金和银金双金属纳米粒子装饰的葡聚糖：抗菌活性的简便合成和多功能可调性。

基于贵金属的纳米颗粒（NPs）由于其良好的抗菌和抗真菌活性以及生物相容性而被认为是潜在的抗菌剂。在这项研究中，我们介绍了一种简单快速的途径来合成银，金和银金双金属NP装饰的葡聚糖。将作为与球形几何形状合成后原样的贵金属基的NP显示出葡聚糖高分散性。用米生黄单胞菌pv测试获得的纳米材料的抗菌和抗真菌性能。稻（Xoo）细菌和稻瘟病菌（M. grisea）） 菌类。葡聚糖中的银含量高的银纳米颗粒和双金属纳米颗粒表现出优异的抑制细菌和真菌生长的活性，而金/葡聚糖的抗微生物作用较弱。可以根据双金属NP中银的含量来调节葡聚糖生物聚合物中的金银双金属NP的抗菌和抗真菌特性。所获得的纳米材料可以为新型抗生素开辟道路。