Lung neuroendocrine neoplasms (LNENs) are rare solid cancers, with most genomic studies including a limited number of samples. Recently, generating the first multi-omic dataset for atypical pulmonary carcinoids and the first methylation dataset for large-cell neuroendocrine carcinomas led us to the discovery of clinically relevant molecular groups, as well as a new entity of pulmonary carcinoids (supra-carcinoids).

中文翻译：

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肺神经内分泌肿瘤的分子图谱


肺神经内分泌肿瘤（LNEN）是罕见的实体癌，大多数基因组研究仅包含有限数量的样本。最近，生成了第一个非典型肺类癌的多组学数据集和第一个大细胞神经内分泌癌的甲基化数据集，使我们发现了临床相关的分子组，以及肺类癌的新实体（超类癌）。