Purpose of review 

The prevalence of metabolic syndrome and hypogonadism continues to rise in the United States and around the world. These two conditions are inexorably linked, and understanding their relationship with each other is key to treating men with either of these conditions.

Recent findings 

Testosterone has been shown to be a key regulator in the maintenance of metabolic homeostasis. A large volume of research has found that testosterone deficiency is closely linked to metabolic syndrome through complex physiologic mechanisms of endothelial dysfunction, inflammation, and glucose metabolism.

Summary 

Interventions through lifestyle modification and testosterone replacement in hypogonadal men may reduce the morbidity and mortality risks associated with metabolic syndrome.

中文翻译：

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性腺机能减退和代谢综合征：回顾和更新

审查目的 

在美国和世界范围内，代谢综合征和性腺机能减退的患病率持续上升。这两个条件无可避免地联系在一起，理解彼此之间的关系是治疗患有这两种条件中任何一个的男人的关键。

最近的发现 

睾丸激素已被证明是维持代谢稳态的关键调节剂。大量研究发现，睾丸激素缺乏症通过内皮功能障碍，炎症和葡萄糖代谢的复杂生理机制与代谢综合征密切相关。

概要 

对性腺机能减退者通过生活方式改变和睾丸激素替代进行干预可以减少与代谢综合征相关的发病率和死亡风险。