ABSTRACT

Introduction

The clinical, social, and economic implications of Parkinson’s disease (PD) are significant; disability occurs leading to a low quality of life (QoL). Information on the QoL of patients with PD and studies on the relationship between QoL and motor and cognitive function are necessary for both research and clinical use to make informed decisions in healthcare and rehabilitation. The aim of this study was to determine which scales are most used to assess QoL in patients with PD.

Area covered

A literature search was conducted in MEDLINE, Scopus, CINAHL, PsycINFO, and Web of Science. Two authors independently identified eligible studies based on predefined inclusion criteria and extracted the data. Study quality and the risk of bias were assessed using the COSMIN checklist.

Expert opinion

116 suitable studies were included, and 42 different instruments were identified. The most frequently used scales were the 39-items and 8-items Parkinson’s Disease Questionnaire (PDQ-39) (PDQ-8). These findings suggest further investigation of existing PD outcome measures would benefit patients, researchers, and clinicians. Validated, universal outcome measures are required to allow comparisons across practice; therefore, we recommend that future researchers use a common set of outcome assessments based on the results of this review.

中文翻译：

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评估帕金森病患者生活质量的工具：系统评价

摘要

介绍

帕金森病 (PD) 的临床、社会和经济影响意义重大；残疾的发生导致生活质量（QoL）低下。PD 患者的生活质量信息以及生活质量与运动和认知功能之间关系的研究对于研究和临床使用都是必要的，以便在医疗保健和康复方面做出明智的决定。本研究的目的是确定哪些量表最常用于评估 PD 患者的生活质量。

覆盖面积

在 MEDLINE、Scopus、CINAHL、PsycINFO 和 Web of Science 中进行了文献检索。两位作者根据预定义的纳入标准独立确定符合条件的研究并提取数据。使用 COSMIN 检查表评估研究质量和偏倚风险。

专家意见

纳入了 116 项合适的研究，并确定了 42 种不同的仪器。最常用的量表是 39 项和 8 项帕金森病问卷 (PDQ-39) (PDQ-8)。这些发现表明，对现有 PD 结果测量的进一步调查将使患者、研究人员和临床医生受益。需要经过验证的、普遍的结果测量，以便在实践中进行比较；因此，我们建议未来的研究人员根据本次审查的结果使用一套通用的结果评估。