Design and synthesis of new donepezil analogs derived from arylpiperazine scaffold as acetylcholinesterase inhibitors,Phosphorus, Sulfur, and Silicon and the Related Elements

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Design and synthesis of new donepezil analogs derived from arylpiperazine scaffold as acetylcholinesterase inhibitors
Phosphorus, Sulfur, and Silicon and the Related Elements ( IF 1.4 ) Pub Date : 2020-10-21 , DOI: 10.1080/10426507.2020.1830773
Zafer Sahin _{1,

2} , Sevde Nur Biltekin ₃ , Emre Fatih Bülbül ₄ , Leyla Yurttas ₂ , Barkin Berk ₁ , Şeref Demirayak ₁

Affiliation

Newly synthesized 4-substituted phenyl-2-(4-substituted phenylpiperazine-1-yl)thiazole derivatives (4a–v) were evaluated in terms of their acetylcholinesterase (AChE) inhibition activities. Twenty-...

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