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Opinion: For now, it’s unethical to use human challenge studies for SARS-CoV-2 vaccine development [Medical Sciences]
Proceedings of the National Academy of Sciences of the United States of America ( IF 9.4 ) Pub Date : 2020-11-17 , DOI: 10.1073/pnas.2021189117
Jeffrey P. Kahn 1 , Leslie Meltzer Henry 1, 2 , Anna C. Mastroianni 3, 4 , Wilbur H. Chen 5 , Ruth Macklin 6
Affiliation  

The prospect of a widely available severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine is an increasingly high priority for an effective response to the coronavirus disease 2019 (COVID-19) pandemic and an area of intense interest and attention for professionals, politicians, and the public alike. The understandable desire for such a vaccine has led to significant discussion and even some planning for the possibility of human challenge studies (HCS) as a tool for accelerating the process for identifying, testing, and developing an effective vaccine (13).

中文翻译:

意见:就目前而言,将人类挑战性研究用于SARS-CoV-2疫苗的开发是不道德的[医学]

有效应对2019年冠状病毒病(COVID-19)大流行,广泛使用的严重急性呼吸系统综合症冠状病毒2(SARS-CoV-2)疫苗的前景日益重要,并且引起了专业人员的广泛关注和关注,政客和公众。这种疫苗可以理解的愿望,导致显著的讨论,甚至一些规划对人类的挑战研究(HCS)作为加速过程中识别,测试和开发有效的疫苗工具的可能性(1 - 3)。
更新日期:2020-11-18
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