Clinical analysis of human umbilical cord mesenchymal stem cell allotransplantation in patients with premature ovarian insufficiency,Cell Proliferation

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Clinical analysis of human umbilical cord mesenchymal stem cell allotransplantation in patients with premature ovarian insufficiency
Cell Proliferation ( IF 5.9 ) Pub Date : 2020-10-29 , DOI: 10.1111/cpr.12938
Long Yan _{1,

2,

3} , Yixuan Wu ₄ , Li Li ₄ , Jun Wu _{1,

3,

5} , Feiyan Zhao ₆ , Zheng Gao ₄ , Wenjing Liu _{3,

5} , Tianda Li _{1,

2,

3} , Yong Fan ₄ , Jie Hao _{1,

3,

5} , Jianqiao Liu ₄ , Hongmei Wang _{1,

2,

3}

Affiliation

Premature ovarian insufficiency (POI) is a refractory disease that seriously affects female fertility. Growing body of evidence has indicated mesenchymal stem cells (MSCs) as promising resources in regenerative medicine. In this study, we treated POI patients with umbilical cord‐derived MSCs (UCMSCs) and then investigated the restoration of ovarian function and clinical outcomes through follow‐ups.

中文翻译：

人脐带间充质干细胞同种异体移植治疗卵巢早衰患者的临床分析

卵巢早衰（POI）是一种严重影响女性生育能力的难治性疾病。越来越多的证据表明间充质干细胞 (MSCs) 是再生医学中很有前景的资源。在这项研究中，我们用脐带源性间充质干细胞 (UCMSCs) 治疗 POI 患者，然后通过随访研究卵巢功能的恢复和临床结果。

更新日期：2020-10-29

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