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A review of a potential and promising probiotic candidate—Akkermansia muciniphila
Journal of Applied Microbiology ( IF 3.2 ) Pub Date : 2020-10-28 , DOI: 10.1111/jam.14911
D. Cheng 1 , M.Z. Xie 2
Affiliation  

Akkermansia muciniphila, a common colonizer in the intestinal mucus layer of humans, has gradually been considered as promising candidate for the next‐generation probiotic, given its physiological benefits from animal and human studies. This article comprehensively reviewed A. muciniphila from the published peer‐reviewed articles in the aspects of its role in the host physiology and commonly consumed food that can boost its abundance, which should provide useful and fundamental information for scientists and engineers and even ordinary consumers. Akkermansia muciniphila is not only a crucial biomarker that indicates the physiology of human beings but also has huge potential to become a probiotic given its physiological benefits in various clinical scenarios. Current barriers in terms of regulations, necessity for large‐scale clinical experiments and production feasibility need to be resolved before A. muciniphila can be widely applied as the next‐generation probiotic.

中文翻译:

潜在的和有前途的益生菌候选物-阿克曼克氏菌的评论

考虑到动物和人体研究的有益效果,Akkermansia muciniphila是人类肠道粘液层中的常见定居者,逐渐被认为是下一代益生菌的有前途的候选者。本文从已发表的同行评审文章中全面审查了黏液曲霉在宿主生理学和可以增加其丰富度的普通食用食品方面的作用,这应该为科学家和工程师甚至普通消费者提供有用的基础信息。墨克阿克曼虫不仅是指示人类生理的重要生物标志物,而且鉴于其在各种临床情况下的生理益处,它还具有成为益生菌的巨大潜力。在规程,大规模临床实验的必要性和生产可行性方面,当前的障碍需要解决,才能将粘菌曲霉广泛用作下一代益生菌。
更新日期:2020-10-28
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