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Genetic analysis of functional longevity in a complete diallel crossing experiment involving four maternal rabbit lines
Journal of Animal Breeding and Genetics ( IF 1.9 ) Pub Date : 2020-10-26 , DOI: 10.1111/jbg.12520
Mohamed Ragab 1, 2 , Manuel Baselga 1 , Ayman G El Nagar 1, 3 , Carlos Mínguez 4 , Juan Pablo Sánchez 5
Affiliation  

In a diallel cross between four maternal lines of rabbits, the four maternal lines and the corresponding crossbred females (does) were evaluated concerning functional longevity, estimating their crossbreeding components. Sixteen genetic groups were produced by using four maternal lines of rabbit (A, V, H and LP (L)). The groups were distributed over 4 Spanish farms. In all farms, the V line was present as the reference group. A total of 7,211 does' longevity records were recorded. Using a Cox proportional hazard model of fixed effects, survival analysis was performed to study longevity analysing the hazard of death or culling. Does from lines A, H and V had similar risks of death or of being culled, and they were more susceptible compared with those from line L. The lowest hazard was associated with L line does. No significant differences were found between the average of all crosses and the V line except when comparing the V line to the cross between A and H lines, favouring the former (1.30 higher risk of replacement for AH animals). Significant differences between reciprocal crosses were observed between VH and HV, in favour of HV (0.72 of relative risk of replacement) and between LH and HL, in favour of HL (0.76 of relative risk). Line V had the highest risk due to the direct genetic effects, and these differences were significant with the lines H (1.40 of relative risk) and L (1.43 of relative risk). The differences in maternal genetic effects were small and not significant except between lines H and V in favour of V line (0.75 of relative risk). The estimated direct heterosis effects do not always follow the same trend but they showed the importance of the crossing between specialized lines to produce crossbred does for intensive meat rabbit production.

中文翻译:

四个母兔品系完整双列杂交实验中功能寿命的遗传分析

在兔子的四个母系之间的双列杂交中,四个母系和相应的杂交雌性(does)就功能寿命进行了评估,估计了它们的杂交成分。使用四个母系兔(A、V、H 和 LP (L))产生了 16 个遗传组。这些团体分布在 4 个西班牙农场。在所有农场中,V 系都作为参照组存在。总共记录了 7,211 条确实的长寿记录。使用固定效应的 Cox 比例风险模型,进行生存分析以研究分析死亡或淘汰风险的寿命。来自 A、H 和 V 系的 dos 具有相似的死亡或被淘汰风险,并且与来自 L 系的 dos 相比,它们更易感。最低风险与 L 系 do 相关。除了将 V 线与 A 和 H 线之间的交叉进行比较时,所有杂交的平均值与 V 线之间没有发现显着差异,有利于前者(AH 动物的替代风险高 1.30)。在 VH 和 HV 之间观察到相互交叉之间的显着差异,有利于 HV(相对风险为 0.72)和在 LH 和 HL 之间,有利于 HL(相对风险为 0.76)。由于直接遗传效应,品系 V 的风险最高,这些差异在品系 H(相对风险为 1.40)和 L(相对风险为 1.43)中显着。除了在 H 和 V 系之间有利于 V 系(相对风险为 0.75)外,母体遗传效应的差异很小且不显着。
更新日期:2020-10-26
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