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Electrospray ionization tandem mass spectrometry of deprotonated dihydrobenzofuran neolignans
Rapid Communications in Mass Spectrometry ( IF 1.8 ) Pub Date : 2020-10-29 , DOI: 10.1002/rcm.8990
Herbert J. Dias 1 , Eduardo J. Crevelin 1 , Vinicius Palaretti 1 , Ricardo Vessecchi 1 , Antônio E.M. Crotti 1
Affiliation  

Although dihydrobenzofuran neolignans (DBNs) display a wide diversity of biological activities, the identification of their in vivo metabolites using liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI‐MS/MS) remains a challenge to be overcome. Recently, ESI‐MS/MS data of protonated DBNs have been reported, but they were shown to be limited due to the scarcity of diagnostic ions.

中文翻译:

去质子化的二氢苯并呋喃新木脂素的电喷雾电离串联质谱

尽管二氢苯并呋喃新木脂(DBN)具有广泛的生物活性,但使用液相色谱/电喷雾串联质谱(LC / ESI-MS / MS)鉴定其体内代谢产物仍然是一个有待克服的挑战。最近,已经报道了质子化DBN的ESI-MS / MS数据,但是由于缺乏诊断离子,因此显示出有限的数据。
更新日期:2020-12-09
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