In vivo investigation of the multi‐exponential T2 decay in human white matter at 7 T: Implications for myelin water imaging at UHF,NMR in Biomedicine

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In vivo investigation of the multi‐exponential T2 decay in human white matter at 7 T: Implications for myelin water imaging at UHF
NMR in Biomedicine ( IF 2.7 ) Pub Date : 2020-10-28 , DOI: 10.1002/nbm.4429
Vanessa Wiggermann _{1,

2,

3} , Alexander L MacKay _{1,

3,

4} , Alexander Rauscher _{1,

2,

3,

5} , Gunther Helms ₆

Affiliation

Multi‐component T₂ mapping using a gradient‐ and spin‐echo (GraSE) acquisition has become standard for myelin water imaging at 3 T. Higher magnetic field strengths promise signal‐to‐noise ratio benefits but face specific absorption rate limits and shortened T₂ times. This study investigates compartmental T₂ times in vivo and addresses advantages and challenges of multi‐component T₂ mapping at 7 T.

中文翻译：

7 T 时人类白质中多指数 T2 衰减的体内研究：对 UHF 髓鞘水成像的影响

使用梯度和自旋回波 (GraSE) 采集的多分量T ₂映射已成为 3 T 髓鞘水成像的标准。更高的磁场强度保证信噪比优势，但面临特定吸收率限制和缩短的T ₂次。该研究调查了体内₂次室室T并解决了多组分T ₂映射在 7 T 时的优势和挑战。

更新日期：2021-01-04

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