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Analysis of expression levels of markers associated with tumor proliferation and angiogenesis in familial adenomatous polyposis
Molecular Genetics & Genomic Medicine ( IF 1.5 ) Pub Date : 2020-10-27 , DOI: 10.1002/mgg3.1534 Zhao Zhang 1 , Dan Wang 2 , Chen Xu 1 , Yuwei Li 1 , Yongjun Yu 1 , Chao Chen 1 , Mingsen Li 1 , Xipeng Zhang 1
Molecular Genetics & Genomic Medicine ( IF 1.5 ) Pub Date : 2020-10-27 , DOI: 10.1002/mgg3.1534 Zhao Zhang 1 , Dan Wang 2 , Chen Xu 1 , Yuwei Li 1 , Yongjun Yu 1 , Chao Chen 1 , Mingsen Li 1 , Xipeng Zhang 1
Affiliation
Familial adenomatous polyposis (FAP) is an autosomal dominant hereditary disease with colorectal adenomatous polyps as the main clinical manifestations. The objective of this study was to analyze and compare the expression levels of tumor proliferation and angiogenesis‐related genes in different tissue sections of FAP patients through qPCR, western blot, and immunohistochemistry (IHC) analysis.
中文翻译:
家族性腺瘤性息肉病中与肿瘤增殖和血管生成相关的标志物的表达水平分析
家族性腺瘤性息肉病(FAP)是一种以大肠腺瘤性息肉为主要临床表现的常染色体显性遗传性疾病。这项研究的目的是通过qPCR,蛋白质印迹和免疫组化(IHC)分析来分析和比较FAP患者不同组织切片中肿瘤增殖和血管生成相关基因的表达水平。
更新日期:2020-12-27
中文翻译:
家族性腺瘤性息肉病中与肿瘤增殖和血管生成相关的标志物的表达水平分析
家族性腺瘤性息肉病(FAP)是一种以大肠腺瘤性息肉为主要临床表现的常染色体显性遗传性疾病。这项研究的目的是通过qPCR,蛋白质印迹和免疫组化(IHC)分析来分析和比较FAP患者不同组织切片中肿瘤增殖和血管生成相关基因的表达水平。