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Dried SARS-CoV-2 virus maintains infectivity to Vero E6 cells for up to 48 h
Veterinary Microbiology ( IF 3.3 ) Pub Date : 2020-10-23 , DOI: 10.1016/j.vetmic.2020.108907
Hyesun Jang , Ted M. Ross

Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is a great concern on both public and veterinary health. Multiple studies showed that the SARS-CoV-2 can persist for few days in wet condition, but it has not been clear whether the virus can maintain the infectivity in dry condition. Thus, we measured the infectious titer of dried SARS-CoV-2 (104 pfu/25 μL droplet) at 0, 0.5, 1, 2, 3, 24, and 48 h. Strikingly, the dried SARS-CoV-2 virus did not lose the infectivity to Vero E6 cells for up to 48 h. Our findings warrants that the drying cannot replace the surface disinfection to prevent transmission via common vehicle or nosocomial infection. Future studies can apply our experimental setting to test the efficacy of diverse disinfecting procedures.



中文翻译:

干燥的SARS-CoV-2病毒可维持对Vero E6细胞的感染性长达48小时

严重的急性呼吸系统综合症冠状病毒2(SARS-CoV-2)是公共和兽医健康都非常关注的问题。多项研究表明,SARS-CoV-2在潮湿条件下可以持续几天,但尚不清楚该病毒是否可以在干燥条件下保持传染性。因此,我们在0、0.5、1、2、3、24和48 h时测量了干燥的SARS-CoV-2(10 4 pfu / 25μL液滴)的感染滴度。令人惊讶的是,干燥的SARS-CoV-2病毒在长达48小时内都没有失去对Vero E6细胞的感染力。我们的发现保证,干燥不能代替表面消毒,以防止通过普通媒介或医院感染传播。未来的研究可以将我们的实验设置用于测试各种消毒程序的功效。

更新日期:2020-10-30
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