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Recent advances of lateral flow immunoassay for mycotoxins detection
Trends in Analytical Chemistry ( IF 11.8 ) Pub Date : 2020-10-24 , DOI: 10.1016/j.trac.2020.116087
Ke-Yu Xing , Shan Shan , Dao-Feng Liu , Wei-Hua Lai

Mycotoxins can accumulate in different organs or tissues by ingestion or skin contact and cause several health problems to humans. Thus, developing a rapid detection method for mycotoxins is important. Lateral flow immunoassay (LFI), with outstanding advantages of convenience and rapidity, is especially suitable for on-site monitoring of mycotoxin contamination in food. Some existing LFI have been considerably improved by combining different kinds of nanosensors or strategies for increasing sensitivity or efficiency. In this review, we summarized nanoparticles-based LFI (e.g., colored, luminescent, or magnetic nanoparticles) for mycotoxins detection. Enzyme, enhancement, or specific recognition elements-based LFI are also briefly explained. The LFI, which allows multiple detections, has paid more attention to mycotoxins preliminary screening. This review focuses on examples of developed LFI for mycotoxins to illustrate novel concepts as screening tools. We believe this review will attract considerable attention and stimulate more distinctive studies for the rapid detection of mycotoxins.



中文翻译:

侧流免疫法检测真菌毒素的最新进展

霉菌毒素可通过食入或皮肤接触而积聚在不同的器官或组织中,并给人类带来一些健康问题。因此,开发真菌毒素的快速检测方法很重要。横向流动免疫测定法(LFI)具有便利和快速的突出优点,特别适合于现场监测食品中的霉菌毒素污染。通过组合不同种类的纳米传感器或提高灵敏度或效率的策略,已经大大改善了一些现有的LFI。在这篇综述中,我们总结了用于霉菌毒素检测的基于纳米粒子的LFI(例如,彩色,发光或磁性纳米粒子)。还简要说明了基于酶,增强或特定识别元素的LFI。允许多次检测的LFI更加关注霉菌毒素的初步筛选。这篇综述着重于为霉菌毒素开发的LFI的实例,以说明作为筛选工具的新颖概念。我们相信这篇综述将吸引相当多的关注,并激发更多有关快速检测真菌毒素的独特研究。

更新日期:2020-11-13
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