当前位置: X-MOL 学术Tissue Cell › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Tissue engineering solutions to replace contractile function during pediatric heart surgery
Tissue & Cell ( IF 2.7 ) Pub Date : 2020-10-23 , DOI: 10.1016/j.tice.2020.101452
Stuart K Williams 1 , Ravi K Birla 2
Affiliation  

Pediatric heart surgery remains challenging due to the small size of the pediatric heart, the severity of congenital abnormalities and the unique characteristics of each case. New tools and technologies are needed to tackle this enormous challenge. Tissue engineering strategies are focused on fabricating contractile heart muscle, ventricles, Fontan pumps and whole hearts, and a transplantable tissue equivalent has tremendous implications in pediatric heart surgery to provide functional cardiac tissue. This technology will prove to be a game-changer in the field of pediatric heart surgery and provide a novel toolkit for pediatric heart surgeons. This review will provide insight into the potential applications of tissue engineering technologies to replace lost contractile function in pediatric patients with heart abnormalities.



中文翻译:

在小儿心脏手术中替代收缩功能的组织工程解决方案

由于小儿心脏的体积小、先天性异常的严重性以及每个病例的独特特征,小儿心脏手术仍然具有挑战性。需要新的工具和技术来应对这一巨大挑战。组织工程策略的重点是制造收缩性心肌、心室、Fontan 泵和整个心脏,可移植的组织等效物在小儿心脏手术中具有巨大的意义,以提供功能性心脏组织。这项技术将证明是小儿心脏外科领域的游戏规则改变者,并为小儿心脏外科医生提供了一个新的工具包。本综述将深入了解组织工程技术在心脏异常儿科患者中替代失去的收缩功能的潜在应用。

更新日期:2020-11-02
down
wechat
bug