当前位置: X-MOL 学术J. Comp. Pathol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Amelanotic Malignant Melanoma in a Himalayan Rex Guinea Pig (Cavia porcellus)
Journal of Comparative Pathology ( IF 0.8 ) Pub Date : 2020-10-23 , DOI: 10.1016/j.jcpa.2020.09.010
Lisa Allnoch 1 , Saskia Köstlinger 2 , Nicole Steffensen 3 , Marion Hewicker-Trautwein 1 , Annika Lehmbecker 1
Affiliation  

A Himalayan Rex guinea pig was presented with a history of nodular, partially ulcerated masses in the subcutis of the left shoulder. Histological examination revealed a garland-like to nodular, infiltrative neoplastic mass of the epidermis and hair follicle epithelium, which obscured the dermoepidermal junction. Neoplastic cells were immunopositive for S100, PNL-2, vimentin and melan-A antigens. No immunolabelling of CD3, CD79, Iba-1 or pancytokeratin was observed. This is the first detailed description of spontaneous amelanotic malignant melanoma in this species.



中文翻译:

喜马拉雅雷克斯豚鼠(Cavia porcellus)的黑色素恶性黑色素瘤

一只喜马拉雅雷克斯豚鼠的左肩皮下组织有结节性、部分溃疡肿块。组织学检查显示表皮和毛囊上皮的花环样至结节性浸润性肿瘤块,掩盖了真皮表皮交界处。肿瘤细胞对 S100、PNL-2、波形蛋白和黑色素 A 抗原呈免疫阳性。没有观察到 CD3、CD79、Iba-1 或全细胞角蛋白的免疫标记。这是对该物种自发性无色素沉着性恶性黑色素瘤的首次详细描述。

更新日期:2020-10-30
down
wechat
bug