MTORC1 activity is critical for tissue regeneration in multiple organs and contexts. In this issue of Developmental Cell, Miao et al. describe upstream regulators of mTORC1 activity which promote paligenosis, a process where mature cells de-differentiate to acquire stem cell activity in the face of injury.

中文翻译：

---

MTORC1和茎的重生

MTORC1活性对于在多个器官和环境中的组织再生至关重要。在本期《发育细胞》中，Miao等人。描述了mTORC1活性的上游调节剂，可促进乳源性病，该过程是成熟细胞去分化以面对损伤获得干细胞活性的过程。