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Biologically Informed Neural Networks Predict Drug Responses
Cancer Cell ( IF 48.8 ) Pub Date : 2020-10-22 , DOI: 10.1016/j.ccell.2020.10.014
Casey S Greene 1 , James C Costello 2
Affiliation  

Deep neural networks often achieve high predictive accuracy on biological problems, but it can be hard to contextualize how and explain why predictions are made. In this issue, Kuenzi et al. model the sensitivity of cancers to drugs using deep neural networks with a hierarchical structure derived from the Gene Ontology.



中文翻译:

生物信息神经网络可预测药物反应

深度神经网络通常可以在生物学问题上实现很高的预测准确性,但是很难根据具体情况来说明和解释做出预测的原因。在本期中,Kuenzi等人。使用具有从基因本体论派生的层次结构的深度神经网络,对癌症对药物的敏感性进行建模。

更新日期:2020-11-09
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