Thousand cankers disease (TCD), is an invasive insect-disease complex caused by the walnut twig beetle, Pityophthorus juglandis, and fungal pathogen, Geosmithia morbida. Semiochemical interruption is a viable option for protecting walnut trees from P. juglandis attack. The goal of this study was to test beetle responses to potential repellent compounds. The results of five, flight-intercept assays are reported. Assays 1–3 tested four compounds at variable release rates: (S)-(−)-verbenone, (R)-(+)-verbenone, racemic chalcogran, and racemic trans-conophthorin. Trapping results indicated that the highest release rate tested for each compound was the most effective in reducing the number of beetles caught. (S)-(−)-Verbenone was the least effective, reducing P. juglandis trap catches by 66%. (R)-(+)-Verbenone reduced the number of P. juglandis by 84%. Neither enantiomer of verbenone performed as well as chalcogran or trans-conophthorin, which both reduced the number of beetles caught by ca. 98%. Following individual assays, the most effective compounds were tested in subtractive-combination assays. Combinations of high release rates for (R)-(+)-verbenone, trans-conophthorin, and two stereoisomers of limonene (tested in a previous study) were tested in two assays. The subtractive-combination assays were inconclusive in that trap catches were similar across all treatments. All combination treatments were highly effective, achieving approximately 99% reduction in the number of beetles caught. Based on the trapping results, commercial availability, and cost of the semiochemicals tested, we conclude that a combination of (R)-(+)-limonene, trans-conophthorin, and (R)-(+)-verbenone constitutes an effective tool for reducing P. juglandis trap catches.

千体鳞癌（TCD）是由核桃树枝状甲虫Pityophthorus juglandis和真菌病原体Geosmithia morbida引起的一种侵入性昆虫疾病复合物。进行化学信息干扰是保护核桃树免受P. juglandis侵袭的可行选择。这项研究的目的是测试甲虫对潜在的驱避剂的反应。报告了五种拦截飞行试验的结果。分析1-3以可变释放速率测试了四种化合物：( S）-（-）-马洛酮，（R）-（+）-马洛酮，消旋查耳格伦和消旋反式-conophthorin。诱捕结果表明，每种化合物的最高释放速率在减少捕获的甲虫数量方面最有效。（S）-（-）-Verbenone效果最差，将P. juglandis诱捕物减少了66％。（- [R ）- （+） -马鞭草烯酮减少的数量P. juglandis由84％。马鞭草酮的对映异构体均不如查尔科兰或反式-conophthorin表现出色，这两者均减少了被ca.捕获的甲虫数量。98％。进行单独的测定后，在减法组合测定中测试了最有效的化合物。（R）-（+）-马洛酮，反式的高释放速率的组合-conophthorin和柠檬烯的两种立体异构体（在先前的研究中进行了测试）在两项分析中进行了测试。消减组合测定没有结论性，因为在所有处理中陷阱捕获量均相似。所有组合处理均非常有效，捕获的甲虫数量减少了约99％。根据诱捕结果，商业可获得性和所测试的化学信息素的成本，我们得出结论，（R）-（+）-柠檬烯，反式-Conophthorin和（R）-（+）-马洛酮的组合构成有效的工具减少P. juglandis陷阱的捕获量。