Surgical treatments have transformed the management of Parkinson’s disease (PD). Therapeutic options available for the management of PD motor complications include deep brain stimulation (DBS), ablative or lesioning procedures (pallidotomy, thalamotomy, subthalamotomy), and dopaminergic medication infusion devices. The decision to pursue these advanced treatment options is typically done by a multidisciplinary team by considering factors such as the patient’s clinical characteristics, efficacy, ease of use, and risks of therapy with a goal to improve PD symptoms and quality of life. DBS has become the most widely used surgical therapy, although there is a re-emergence of interest in ablative procedures with the introduction of MR-guided focused ultrasound. In this article, we review DBS and lesioning procedures for PD, including indications, selection process, and management strategies.

手术治疗改变了帕金森病 (PD) 的治疗方法。可用于治疗 PD 运动并发症的治疗方案包括深部脑刺激 (DBS)、消融或病变手术（苍白球切开术、丘脑切开术、丘脑下切开术）和多巴胺能药物输注装置。寻求这些先进治疗方案的决定通常是由多学科团队做出的，他们会考虑患者的临床特征、疗效、易用性和治疗风险等因素，以改善 PD 症状和生活质量。尽管随着 MR 引导聚焦超声的引入，人们对消融手术重新产生了兴趣，但 DBS 已成为使用最广泛的手术疗法。在本文中，我们回顾了 DBS 和 PD 病变程序，包括适应症、选择过程和管理策略。