• The capability of gold nanomaterials to mimic enzyme activities offers new approaches for diagnosis and treatment in the field of biomedicine, which are discussed in this review.

• Controlling the physicochemical properties of the nanomaterials (size, morphology and surface chemistry) remains the first obstacle for endeavouring real-life applications.

• Numerous examples of ex vivo applications in the field of diagnosis are a reality today, whereas further controlling side effects is required for in vivo applications like tumour treatment or intracellular ROS level control.

中文翻译：

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金纳米酶：从概念到生物医学应用

• 金纳米材料模拟酶活性的能力为生物医学领域的诊断和治疗提供了新的方法，本文将对此进行讨论。

• 控制纳米材料的物理化学性质（尺寸、形态和表面化学）仍然是实现实际应用的第一个障碍。

• 如今，在诊断领域中体外应用的众多例子已成为现实，而体内应用（如肿瘤治疗或细胞内 ROS 水平控制）则需要进一步控制副作用。