Built environments, occupants, and microbiomes constitute a system of ecosystems with extensive interactions that impact one another. Understanding the interactions between these systems is essential to develop strategies for effective management of the built environment and its inhabitants to enhance public health and well-being. Numerous studies have been conducted to characterize the microbiomes of the built environment. This review summarizes current progress in understanding the interactions between attributes of built environments and occupant behaviors that shape the structure and dynamics of indoor microbial communities. In addition, this review also discusses the challenges and future research needs in the field of microbiomes of the built environment that necessitate research beyond the basic characterization of microbiomes in order to gain an understanding of the causal mechanisms between the built environment, occupants, and microbiomes, which will provide a knowledge base for the development of transformative intervention strategies toward healthy built environments. The pressing need to control the transmission of SARS-CoV-2 in indoor environments highlights the urgency and significance of understanding the complex interactions between the built environment, occupants, and microbiomes, which is the focus of this review.

建成的环境，居住者和微生物群落构成了一个生态系统，相互之间有着广泛的相互作用。了解这些系统之间的相互作用对于制定有效管理建筑环境及其居民的策略以提高公共健康和福祉至关重要。已经进行了许多研究来表征建筑环境的微生物组。这篇综述总结了在了解建筑环境属性与塑造室内微生物群落结构和动力学的乘员行为之间相互作用方面的最新进展。此外，这篇综述还讨论了建筑环境微生物群落领域中的挑战和未来的研究需求，这些挑战和研究需要对微生物群落的基本特征进行研究，以了解建筑环境，居住者和微生物群落之间的因果机制，为开发针对健康建筑环境的变革性干预策略提供知识基础。迫切需要控制SARS-CoV-2在室内环境中的传播，突显了理解建筑环境，居住者和微生物群落之间复杂相互作用的紧迫性和重要性，这是本文的重点。这将为开发针对健康建筑环境的变革性干预策略提供知识基础。迫切需要控制SARS-CoV-2在室内环境中的传播，突显了理解建筑环境，居住者和微生物群落之间复杂相互作用的紧迫性和重要性，这是本文的重点。这将为开发针对健康建筑环境的变革性干预策略提供知识基础。迫切需要控制SARS-CoV-2在室内环境中的传播，突显了理解建筑环境，居住者和微生物群落之间复杂相互作用的紧迫性和重要性，这是本文的重点。