The investigation of cell death mechanisms is one of the fastest growing areas of modern biomedicine. A particular interest in this research topic arose in 1972 after publication of an article by Kerr, Wyllie, and Currie, in which apoptosis, one of the types of cell death, was first considered as a basic biological phenomenon regulating tissue homeostasis. Several Russian groups involved in the investigation of the mechanisms of radiation-induced cell death have drawn attention to the similarity between these two mechanisms. Unfortunately, these studies have been for a long time inaccessible to the international scientific community. These introductory remarks attempt to restore the chain of events that have taken place during the past 50 years.

中文翻译：

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程序性细胞死亡：来自俄罗斯的历史笔记

细胞死亡机制的研究是现代生物医学发展最快的领域之一。1972 年 Kerr、Wyllie 和 Currie 发表了一篇文章后，人们对这一研究课题产生了特别的兴趣，其中细胞死亡的一种类型凋亡首先被认为是调节组织稳态的基本生物学现象。几个参与研究辐射诱导细胞死亡机制的俄罗斯团体已经引起人们对这两种机制之间相似性的关注。不幸的是，这些研究长期以来一直无法为国际科学界所接受。这些介绍性评论试图还原过去 50 年发生的一系列事件。