Breast cancer cell lines consist of bulk tumor cells and a small proportion of stem-like cells. While the bulk cells are known to express a distinct combination of Eph receptors and ephrin ligands, the transcript profiles of stem-like cells in these cell lines have not been adequately characterized. The aim of this study was to determine Eph receptor/ephrin ligand profiles of cancer stem cells specific to a triple negative breast carcinoma cell line.

中文翻译：

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来自浸润性乳腺癌细胞系MDA-MB-231的干细胞样细胞表达一套不同的Eph受体和Ephrin配体。

乳腺癌细胞系由大量肿瘤细胞和一小部分干细胞组成。虽然已知这些大细胞表达Eph受体和ephrin配体的独特组合，但尚未充分表征这些细胞系中干细胞的转录谱。这项研究的目的是确定特异于三阴性乳腺癌细胞系的癌症干细胞的Eph受体/ ephrin配体谱。