In order to expand the application of chitosan in cosmetics, it was modified with vitamin C to prepare a chitosan/vitamin C complex (CSVC complex), which was characterized using ultraviolet-visual, Fourier transform infrared, and differential scanning calorimetry techniques. Its hygroscopicity, moisture retention, antioxidant and antibacterial activities, and environmental stability were also determined. The results showed that a mass ratio of chitosan to vitamin C of 1:1 that reacted at 25℃ for 90 minutes in a medium of isopropanol–water, away from light, with the unreacted vitamin C being removed by dialysis gave a white powder (CSVC complex) after freeze-drying. The CSVC complex had good water solubility, a viscosity average molecular weight of 233.7 kDa, and a vitamin C content of 22.64%. Structure characterization confirmed that the CSVC complex was composed of the amine (C-2 position) of chitosan and the hydroxyl group (C-3 position) of vitamin C by electrostatic attraction. The complex had a significantly better scavenging effect on hydroxyl free radicals than chitosan, and the minimum inhibitory concentration against Escherichia coli was 5 mg/mL. Its moisturizing and hygroscopic properties were better than chitosan, and its stability was better than that of vitamin C. These results provide the basis for the CSVC complex as a multifunctional raw material for cosmetic use because of its antioxidant, moisturizing, antibacterial, and film-forming properties.

为了扩大壳聚糖在化妆品中的应用，使用维生素C对其进行了改性，以制备壳聚糖/维生素C复合物（CSVC复合物），使用紫外-可见，傅里叶变换红外和差示扫描量热技术对其进行表征。还测定了其吸湿性，水分保持性，抗氧化剂和抗菌活性以及环境稳定性。结果表明，壳聚糖与维生素C的质量比为1：1，在异丙醇-水介质中，于避光条件下，在25℃下反应90分钟，透析后除去未反应的维生素C，得到白色粉末（ CSVC复合物）冷冻干燥后。CSVC复合物具有良好的水溶性，粘均分子量为233.7 kDa，维生素C含量为22.64％。结构表征证实，通过静电吸引，CSVC复合物由壳聚糖的胺（C-2位）和维生素C的羟基（C-3位）组成。与壳聚糖相比，该复合物对羟基自由基的清除作用明显更好，并且对壳聚糖的最小抑制浓度大肠杆菌为5 mg / mL。它的保湿和吸湿性能优于壳聚糖，并且其稳定性优于维生素C。这些结果为CSVC复合物作为化妆品多功能原料提供了基础，因为它具有抗氧化剂，保湿，抗菌和成膜作用，成型性能。