A 3-mo-old, female Boer goat was presented because of respiratory difficulties. Tachypnea and inspiratory dyspnea were noted during physical examination. Thoracic radiographs were unremarkable; however, upper airway and nasal passage radiographs revealed a soft tissue mass within the nasal passages. The patient underwent cardiorespiratory arrest and did not respond to resuscitation efforts during endoscopy. A large, pedunculated, semi-firm mass originated from the soft palate and obstructed 90% of the nasopharynx on autopsy. Histologically, the mass was composed of primitive cells that multifocally formed tubules and glomeruloid structures intermingled with areas of fusiform and blastemal cells. The neoplastic cells were positive for cytokeratin (tubular and glomeruloid cells), vimentin (fusiform population and blastemal cells), and Wilms tumor 1 protein (glomeruloid structures) on immunohistochemistry, consistent with a triphasic nephroblastoma. To our knowledge, nasopharyngeal nephroblastoma has not been reported previously in any species.

一只 3 个月大的雌性波尔山羊因呼吸困难而出现。体格检查时发现呼吸急促和吸气性呼吸困难。胸片无异常；然而，上呼吸道和鼻道射线照片显示鼻道内有软组织肿块。患者经历了心肺骤停，在内窥镜检查期间对复苏努力没有反应。一个大的、有蒂的、半坚硬的肿块起源于软腭，在尸检中阻塞了 90% 的鼻咽。组织学上，肿块由原始细胞组成，这些原始细胞多灶性形成小管和肾小球结构，与梭状细胞和胚细胞区域混合。肿瘤细胞的细胞角蛋白（管状和肾小球细胞）、波形蛋白（梭形细胞群和胚细胞）、和 Wilms 肿瘤 1 蛋白（肾小球结构）在免疫组织化学上，与三相肾母细胞瘤一致。据我们所知，以前没有任何物种报告过鼻咽肾母细胞瘤。