Objective:

To identify patterns (“classes”) of outcomes for adults with and without childhood ADHD.

Method:

Subjects were 232 childhood ADHD cases and 335 non-ADHD referents from a 1976 to 1982 birth cohort. We used latent class analyses to identify classes based on a broad array of adult psychosocial outcomes and determined the proportion of subjects with childhood ADHD within each class.

Results:

A three class solution provided optimal model fit; classes were termed “good,” “intermediate,” and “poor” functioning. Subjects with childhood ADHD comprised 62.8% of the “poor,” 53.5% of the “intermediate,” and 24.9% of the “good” functioning class. The “poor” functioning class was distinguished by increased likelihood of legal trouble and substance use disorders and included more individuals with childhood ADHD and psychiatric disorder than the “intermediate” class (45.5% vs. 30.6%).

Conclusion:

Children with ADHD are at risk for adverse adult outcomes in multiple domains and co-morbid childhood psychiatric disorders increase risk.

中文翻译：

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患有多动症的儿童面临一系列跨功能领域的不良成人结果的风险：基于人群的出生队列研究的结果

客观的：

确定患有和不患有儿童多动症的成年人的结果模式（“类别”）。

方法：

受试者是 1976 年至 1982 年出生队列中的 232 名儿童 ADHD 病例和 335 名非 ADHD 参考对象。我们使用潜在类别分析来确定基于广泛的成人心理社会结果的类别，并确定每个类别中患有儿童多动症的受试者的比例。

结果：

三类解决方案提供了最佳模型拟合；班级被称为“好”、“中等”和“差”的功能。患有儿童多动症的受试者包括 62.8% 的“差”、53.5% 的“中级”和 24.9% 的“良好”功能类。“差”功能类别的特点是法律纠纷和物质使用障碍的可能性增加，并且包括比“中级”类别更多的儿童多动症和精神疾病患者（45.5% 对 30.6%）。

结论：

患有 ADHD 的儿童在多个领域面临成人不良结局的风险，并且合并的儿童精神疾病会增加风险。