Starting with the launch of the Human Genome Project three decades ago, and continuing after its completion in 2003, genomics has progressively come to have a central and catalytic role in basic and translational research. In addition, studies increasingly demonstrate how genomic information can be effectively used in clinical care. In the future, the anticipated advances in technology development, biological insights, and clinical applications (among others) will lead to more widespread integration of genomics into almost all areas of biomedical research, the adoption of genomics into mainstream medical and public-health practices, and an increasing relevance of genomics for everyday life. On behalf of the research community, the National Human Genome Research Institute recently completed a multi-year process of strategic engagement to identify future research priorities and opportunities in human genomics, with an emphasis on health applications. Here we describe the highest-priority elements envisioned for the cutting-edge of human genomics going forward-that is, at 'The Forefront of Genomics'.

中文翻译：

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在基因组学前沿改善人类健康的战略愿景

从 30 年前启动人类基因组计划开始，到 2003 年完成后，基因组学逐渐在基础和转化研究中发挥核心和催化作用。此外，越来越多的研究证明基因组信息可以如何有效地用于临床护理。未来，技术发展、生物学见解和临床应用（以及其他）的预期进步将导致基因组学更广泛地融入生物医学研究的几乎所有领域，将基因组学纳入主流医疗和公共卫生实践，以及基因组学与日常生活的日益关联。代表研究界，国家人类基因组研究所最近完成了一项为期多年的战略参与过程，以确定人类基因组学的未来研究重点和机会，重点是健康应用。在这里，我们描述了为未来人类基因组学前沿所设想的最高优先级元素——即“基因组学的前沿”。