Purpose: In this brief report, we ask whether women’s interpretation of breast cancer risk based on their low likelihood of carrying a BRCA1/2 mutation is associated with their information-sharing behavior, and whether misinterpretation is associated with motives for sharing the result. Methods: Women in mammography clinics who completed a brief family history assessment and deemed to be at low likelihood of carrying a BRCA1/2 mutation were asked to complete a 1-time online survey between June 2016 and January 2017. Results: One-third (44/148) of women shared their family history screen result with someone in their social network. Result information was shared largely with a first-degree female relative to express feelings of relief (77%, 33/43). There were no differences in likelihood of sharing based on breast cancer risk interpretation. However, women who misinterpreted the implications of the result for general breast cancer risk reported more motives to share the result with their social network than those who accurately interpreted their breast cancer risk. Conclusions: As family history-based screening for hereditary breast cancer is broadly implemented, the communication needs of the majority of women who will be unlikely of carrying a BRCA1/2 mutation must be considered. The motives of women who misinterpreted the implications of this result for breast cancer risk suggest the possibility that miscommunication could be spread to the broader family network.

中文翻译：

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对遗传性乳腺癌风险的误解及其与携带BRCA1/2突变可能性低的女性信息共享动机的关联

目的：在这份简短的报告中，我们询问女性基于携带 BRCA1/2 突变的低可能性对乳腺癌风险的解释是否与她们的信息共享行为有关，以及误解是否与分享结果的动机有关。方法：要求乳房 X 光检查诊所完成简短家族史评估并被认为携带 BRCA1/2 突变的可能性较低的女性在 2016 年 6 月至 2017 年 1 月期间完成 1 次在线调查。结果：三分之一（ 44/148) 的女性与社交网络中的某个人分享了她们的家族史筛查结果。结果信息主要与一级女性亲属共享，以表达解脱的感觉 (77%, 33/43)。基于对乳腺癌风险的解释，分享的可能性没有差异。然而，与准确解释其乳腺癌风险的女性相比，误解结果对一般乳腺癌风险的影响的女性报告说，在社交网络上分享结果的动机更多。结论：随着基于家族史的遗传性乳腺癌筛查的广泛实施，必须考虑大多数不太可能携带 BRCA1/2 突变的女性的交流需求。误解这一结果对乳腺癌风险影响的女性的动机表明，沟通不畅可能会蔓延到更广泛的家庭网络。随着基于家族史的遗传性乳腺癌筛查的广泛实施，必须考虑大多数不太可能携带 BRCA1/2 突变的女性的交流需求。误解这一结果对乳腺癌风险影响的女性的动机表明，沟通不畅可能会蔓延到更广泛的家庭网络。随着基于家族史的遗传性乳腺癌筛查的广泛实施，必须考虑大多数不太可能携带 BRCA1/2 突变的女性的交流需求。误解这一结果对乳腺癌风险影响的女性的动机表明，沟通不畅可能会蔓延到更广泛的家庭网络。