Theranostic Prospects of Graphene Quantum Dots in Breast Cancer,ACS Biomaterials Science & Engineering

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Theranostic Prospects of Graphene Quantum Dots in Breast Cancer
ACS Biomaterials Science & Engineering ( IF 5.4 ) Pub Date : 2020-10-26 , DOI: 10.1021/acsbiomaterials.0c01045
Rahul S. Tade ₁ , Pravin O. Patil ₁

Affiliation

Breast cancer (BC) is increasing as a significant cause of mortality among women. In this context, early diagnosis and treatment strategies for BC are being developed by researchers at the cellular level using advanced nanomaterials. However, immaculate etiquette is the prerequisite for their implementation in clinical practice. Considering the stolid nature of cancer, combining diagnosis and therapy (theranostics) using graphene quantum dots (GQDs) is a prime focus and challenge for researchers. In a nutshell, GQDs is a new shining star among various fluorescent materials, which has acclaimed fame in a short duration in materials science and the biomedical field as well. From this perspective, we review various strategies in BC treatment using GQDs alone or in combination. In addition, the photophysical properties of GQDs explored in photothermal therapy, hyperthermia therapy, and photodynamic therapy are also discussed. Moreover, we also focus on the strategic use of GQDs both as drug carriers and as combinatorial-guided drug delivery motifs. This Review provides an update for the scientific community to plan and expand advanced theranostic horizons in BC using GQDs.

中文翻译：

石墨烯量子点在乳腺癌中的治疗学前景

乳腺癌（BC）正在增加，是妇女死亡的重要原因。在这种情况下，研究人员正在细胞水平上使用先进的纳米材料开发出BC的早期诊断和治疗策略。然而，完美的礼节是其在临床实践中实施的前提。考虑到癌症的隐秘性质，使用石墨烯量子点（GQD）组合诊断和治疗（热学检查）是研究人员的主要重点和挑战。简而言之，GQD是各种荧光材料中的一颗新星，它在材料科学和生物医学领域的短时间内广受赞誉。从这个角度出发，我们回顾了单独或组合使用GQD进行BC治疗的各种策略。此外，还讨论了在光热疗法，热疗疗法和光动力疗法中探索的GQD的光物理特性。此外，我们还专注于GQD的战略用途，既可以作为药物载体，也可以作为组合指导的药物递送主题。本评论为科学界提供了更新，以计划和扩展使用GQD在卑诗省开展的先进的岩石学研究。

更新日期：2020-11-09

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