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Numerical modeling of MoS2–graphene bilayer-based high-performance surface plasmon resonance sensor: structure optimization for DNA hybridization
Optical Engineering ( IF 1.1 ) Pub Date : 2020-10-27 , DOI: 10.1117/1.oe.59.10.105105
Md. Biplob Hossain 1
Affiliation  

Abstract. We present a MoS2–graphene bilayer-based high-performance refractive index surface plasmon resonance (SPR) sensor applying an angular interrogation technique. We used it for inspecting the reflected optical signal from the sensing medium. For enhancing the sensor angular sensitivity (S), signal-to-noise ratio (SNR), and quality factor (QF), we undertook some steps sequentially. First, the impact of gold layer thickness was investigated and optimized to 40 nm. Second, the MoS2 and graphene coating layers were optimized to four and three, respectively. Finally, the minimum reflectance and SPR angle were identified with this optimum structure. It is seen that the angular sensitivity of this optimum structure improved to an excellent value of 130 deg-RIU − 1 along with an improved angular SNR of 1.37 and QF of 17.02 RIU − 1. Then we compared the proposed sensor with the existing works in terms of angular sensitivity, SNR, and QF to prove its effective application. Finally, an analysis of DNA hybridization is presented as an application of the proposed structure. Our offered configuration is capable of recognizing absorption of DNAs by means of the attenuated total reflection method. The effective refractive index of the sensing medium alters because of the absorption of various concentrated DNAs. Computational investigation demonstrates that the change of SPR angle and minimum reflectance for mismatched DNA strands is inconsiderable, though it is significant for complementary DNA strands, which is crucial for the sensing of accurate DNA hybridization.

中文翻译:

基于 MoS2-石墨烯双层的高性能表面等离子体共振传感器的数值模拟:DNA 杂交的结构优化

摘要。我们提出了一种应用角度询问技术的基于 MoS2-石墨烯双层的高性能折射率表面等离子体共振 (SPR) 传感器。我们用它来检查来自传感介质的反射光信号。为了提高传感器角度灵敏度 (S)、信噪比 (SNR) 和品质因数 (QF),我们依次采取了一些步骤。首先,研究了金层厚度的影响,并将其优化为 40 nm。其次,MoS2 和石墨烯涂层分别优化为四个和三个。最后,用这种最佳结构确定了最小反射率和 SPR 角。可以看出,这种最佳结构的角度灵敏度提高到了 130 deg-RIU - 1 的优异值,同时提高了 1.37 的角度 SNR 和 17.02 RIU - 1 的 QF。然后我们在角度灵敏度、SNR 和 QF 方面将所提出的传感器与现有工作进行了比较,以证明其有效应用。最后,将 DNA 杂交分析作为所提出结构的应用。我们提供的配置能够通过衰减全反射方法识别 DNA 的吸收。由于各种浓缩 DNA 的吸收,传感介质的有效折射率会发生变化。计算研究表明,错配 DNA 链的 SPR 角和最小反射率的变化是微不足道的,尽管它对互补 DNA 链很重要,这对于检测准确的 DNA 杂交至关重要。和 QF 以证明其有效应用。最后,将 DNA 杂交分析作为所提出结构的应用。我们提供的配置能够通过衰减全反射方法识别 DNA 的吸收。由于各种浓缩 DNA 的吸收,传感介质的有效折射率会发生变化。计算研究表明,错配 DNA 链的 SPR 角和最小反射率的变化是微不足道的,尽管它对互补 DNA 链很重要,这对于检测准确的 DNA 杂交至关重要。和 QF 以证明其有效应用。最后,将 DNA 杂交分析作为所提出结构的应用。我们提供的配置能够通过衰减全反射方法识别 DNA 的吸收。由于各种浓缩 DNA 的吸收,传感介质的有效折射率会发生变化。计算研究表明,错配 DNA 链的 SPR 角和最小反射率的变化是微不足道的,尽管它对互补 DNA 链很重要,这对于检测准确的 DNA 杂交至关重要。我们提供的配置能够通过衰减全反射方法识别 DNA 的吸收。由于各种浓缩 DNA 的吸收,传感介质的有效折射率会发生变化。计算研究表明,错配 DNA 链的 SPR 角和最小反射率的变化是微不足道的,尽管它对互补 DNA 链很重要,这对于检测准确的 DNA 杂交至关重要。我们提供的配置能够通过衰减全反射方法识别 DNA 的吸收。由于各种浓缩 DNA 的吸收,传感介质的有效折射率会发生变化。计算研究表明,错配 DNA 链的 SPR 角和最小反射率的变化是微不足道的,尽管它对互补 DNA 链很重要,这对于检测准确的 DNA 杂交至关重要。
更新日期:2020-10-27
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