当前位置: X-MOL 学术J. Neurophysiol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
What are the gray and white matter volumes of the human spinal cord?
Journal of Neurophysiology ( IF 2.1 ) Pub Date : 2020-10-21 , DOI: 10.1152/jn.00413.2020
Simon Henmar 1 , Erik B Simonsen 1 , Rune W Berg 1
Affiliation  

The gray matter of the spinal cord is the seat of somata of various types of neurons devoted to the sensory and motor activities of the limbs and trunk as well as a part of the autonomic nervous system. The volume of the spinal gray matter is an indicator of the local neuronal processing and this can decrease due to atrophy associated with degenerative diseases and injury. Nevertheless, the absolute volume of the human spinal cord has rarely been reported, if ever. Here, we use high-resolution magnetic resonance imaging, with a cross-sectional resolution of 50 x 50 μm^2 and a voxel size of 0.0005 mm^3, to estimate the total gray and white matter volume of a post mortem human female spinal cord. Segregation of gray and white matter was accomplished using deep learning image segmentation. Further, we include data from a male spinal cord of a previously published study. The gray and white matter volumes were found to be 2.87 and 11.33 ml, respectively for the female and 3.55 and 19.33 ml, respectively for a male. The gray and white matter profiles along the vertebral axis were found to be strikingly similar and the volumes of the cervical, thoracic and lumbosacral sections were almost equal.

中文翻译:

人类脊髓的灰质和白质体积是多少?

脊髓灰质是各种神经元胞体的所在地,负责四肢和躯干的感觉和运动活动,也是自主神经系统的一部分。脊髓灰质的体积是局部神经元处理的指标,由于与退行性疾病和损伤相关的萎缩,这可能会减少。然而,人类脊髓的绝对体积很少被报道,如果有的话。在这里,我们使用高分辨率磁共振成像,横截面分辨率为 50 x 50 μm^2,体素大小为 0.0005 mm^3,来估计死后人类女性脊柱的灰白质总量绳索。使用深度学习图像分割完成灰质和白质的分离。更远,我们纳入了先前发表的一项研究的男性脊髓数据。女性的灰质和白质体积分别为 2.87 和 11.33 毫升,男性分别为 3.55 和 19.33 毫升。发现沿椎轴的灰质和白质分布惊人地相似,颈椎、胸椎和腰骶部的体积几乎相等。
更新日期:2020-10-27
down
wechat
bug