Four new pyrrole alkaloids, named amokoens A–D (1–4), together with three known compounds (5–7) were isolated from the rhizomes of Amomum koenigii. Their structures and absolute configurations were established by spectroscopic data, including 1D and 2D NMR, and the optical rotation calculations. All the isolates were evaluated for their effects on nitric oxide (NO) production in lipopolysaccharide-induced RAW264.7 macrophages. Compounds 1–7 inhibited NO production ranging from 27.1 to 82.4% at a concentration of 100 μM, and compounds 5 and 6 showed efficacious inhibitory activities with IC₅₀ values of 42.2 and 69.3 µM, respectively.

四个新的吡咯生物碱，命名amokoens A-d（1 - 4），加上三个已知化合物（5 - 7）从根茎分离砂仁koenigii。它们的结构和绝对构型是通过光谱数据（包括1D和2D NMR）以及旋光度计算确定的。评价所有分离物对脂多糖诱导的RAW264.7巨噬细胞中一氧化氮（NO）产生的影响。化合物1 - 7抑制NO产生，在100的浓度为27.1至82.4％  μ M和化合物5和6显示有效的抑制活性与IC _50个42.2 69.3值 μ分别男，。