Lanthanide-Activated Nanoparticles: A Toolbox for Bioimaging, Therapeutics, and Neuromodulation,Accounts of Chemical Research

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Lanthanide-Activated Nanoparticles: A Toolbox for Bioimaging, Therapeutics, and Neuromodulation
Accounts of Chemical Research ( IF 16.4 ) Pub Date : 2020-10-26 , DOI: 10.1021/acs.accounts.0c00513
Zhigao Yi _{1,

2} , Zichao Luo _{1,

2} , Xian Qin ₁ , Qiushui Chen ₁ , Xiaogang Liu _{1,

2,

3}

Affiliation

Owing to their unique features, the past decade has witnessed rapid developments of lanthanide-activated nanoparticles for biological applications. These include highly tunable upconverting and downshifting photoluminescence when illuminated in deep tissue, excellent photostability against blinking and bleaching effects, biocompatibility through versatile surface modification, and ease of achieving multifunctionality, as well as satisfactory signal output. These attributes make lanthanide-doped nanoparticles an ideal toolbox for advanced bioimaging and next-generation therapeutics.

中文翻译：

镧系元素激活的纳米颗粒：用于生物成像，治疗和神经调节的工具箱

由于其独特的功能，过去十年见证了用于生物应用的镧系元素活化纳米粒子的快速发展。这些功能包括在深层组织中照明时高度可调的上转换和下移光致发光，出色的抗闪烁和漂白效果的光稳定性，通过通用的表面修饰实现的生物相容性以及易于实现的多功能性以及令人满意的信号输出。这些特性使掺杂镧系元素的纳米颗粒成为用于高级生物成像和下一代治疗剂的理想工具箱。

更新日期：2020-11-17

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