A type of polymer/ceramic coating was introduced on a magnesium-based nanocomposite, and the nanocomposite was evaluated for implant applications. The microstructure, corrosion, and bioactivity of the coated and uncoated samples were assessed. Mechanical alloying followed by sintering was applied to fabricate the Mg-3Zn-0.5Ag-15NiTi nanocomposite substrate. Moreover, different contents of poly(lactic-co-glycolic acid) (PLGA) coatings were studied, and 10wt% of PLGA content was selected. The scanning electron microscopy (SEM) images of the bulk nanocomposite showed an acceptable homogenous dispersion of the NiTi nanoparticles (NPs) in the Mg-based matrix. In the in vitro bioactivity evaluation, following the immersion of the uncoated and coated samples in a simulated body fluid (SBF) solution, the Ca/P atomic ratio demonstrated that the apatite formation amount on the coated sample was greater than that on the uncoated nanocomposite. Furthermore, assessing the corrosion resistance indicated that the coatings on the Mg-based substrate led to a corrosion current density (i_corr) that was considerably lower than that of the substrate. Such a condition revealed that the coating would provide an obstacle for the corrosion. Based on this study, the PLGA/hardystonite (HT) composite-coated Mg-3Zn-0.5Ag-15NiTi nanocomposite may be suitably applied as an orthopedic implant biomaterial.

将一种聚合物/陶瓷涂层引入到镁基纳米复合材料上，并对纳米复合材料的植入应用进行了评估。评估了涂层和未涂层​​样品的微观结构，腐蚀和生物活性。机械合金化然后烧结被应用于制造Mg-3Zn-0.5Ag-15NiTi纳米复合材料基底。此外，研究了聚乳酸-乙醇酸（PLGA）涂料的不同含量，并选择了10wt％的PLGA含量。体纳米复合材料的扫描电子显微镜（SEM）图像显示，NiTi纳米颗粒（NPs）在基于Mg的基质中可接受的均匀分散。在体外生物活性评估后，将未涂覆和涂覆的样品浸入模拟体液（SBF）溶液中后，Ca / P原子比表明，涂覆样品上的磷灰石形成量大于未涂覆纳米复合材料上的磷灰石形成量。此外，评估耐腐蚀性表明，基于Mg的基材上的涂层导致的腐蚀电流密度（i _corr）大大低于基材的腐蚀电流密度。这种情况表明涂层将为腐蚀提供障碍。根据这项研究，PLGA /硬钙石（HT）复合涂层Mg-3Zn-0.5Ag-15NiTi纳米复合材料可以适当地用作骨科植入物生物材料。