We use a simple two-trial odor recognition paradigm to test memory duration, span, and specificity in adult mice. Our paradigm allows mice to encode and/or recall multiple odors in one trial and necessitates no training or food/water deprivation. We show that this paradigm can be used for encoding and/or testing of multiple odors in single trials, leading to shorter behavioral testing. Using this simple paradigm, we show that mice can remember a single odor for up to 10 but no more than 15 min and two odors for up to 5 min. Mice could not remember 3 odors at any delays tested here. We also show that specificity for the encoded odor decreases as delay increases. Our results are important for setting baseline levels of testing for experiments in which memory parameters are expected to be modulated. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

中文翻译：

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小鼠的嗅觉识别记忆取决于任务参数。

我们使用简单的两次试验气味识别范式来测试成年小鼠的记忆持续时间、跨度和特异性。我们的范例允许小鼠在一次试验中编码和/或回忆多种气味，并且不需要训练或食物/水剥夺。我们表明，这种范式可用于在单次试验中编码和/或测试多种气味，从而缩短行为测试时间。使用这个简单的范例，我们表明小鼠可以记住一种气味长达 10 分钟但不超过 15 分钟，并且可以记住两种气味长达 5 分钟。在这里测试的任何延迟，小鼠都无法记住 3 种气味。我们还表明，随着延迟的增加，对编码气味的特异性降低。我们的结果对于为期望调节记忆参数的实验设置基线测试水平很重要。（PsycInfo 数据库记录 (c) 2020 APA，