Structural Transition Dynamics in Carbon Electrode‐Based Single‐Molecule Junctions,Chinese Journal of Chemistry

当前位置： X-MOL 学术 › Chin. J. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Structural Transition Dynamics in Carbon Electrode‐Based Single‐Molecule Junctions
Chinese Journal of Chemistry ( IF 5.5 ) Pub Date : 2020-10-22 , DOI: 10.1002/cjoc.202000529
Peihui Li ₁ , Chuancheng Jia ₁ , Xuefeng Guo _{1,

2}

Affiliation

Monitoring the structural transitions of individual molecules is of great significance because it helps to in depth explore the properties of molecules and provide diverse possibilities for molecular applications in the fields of chemistry, biology and material science. This review summarizes the strategy of using single‐molecule electrical approaches to study molecular structure transitions at the single‐molecule level in real time. Specifically, through the use of stable single‐molecule devices for real‐time electrical monitoring, the process of molecular structure transitions of a single molecule can be investigated, which helps to explore the nature of molecules in chemical and biological systems. In particular, the detection methods have been extended to the investigation of biological macromolecules for monitoring the conformational changes of nucleotide chains in different systems, such as double helix DNA, aptamer and DNA enzyme. In the end, we discuss the future challenges of probing structural transitions of single molecules, and provide prospects for further breakthroughs in this field.

中文翻译：

碳电极基单分子结的结构转变动力学

监测单个分子的结构转变具有重要意义，因为它有助于深入探索分子的特性，并为化学，生物学和材料科学领域中的分子应用提供各种可能性。这篇综述总结了使用单分子电方法实时研究单分子水平上的分子结构转变的策略。具体而言，通过使用稳定的单分子设备进行实时电监控，可以研究单个分子的分子结构转变过程，这有助于探索化学和生物系统中分子的性质。特别是，该检测方法已扩展到生物大分子研究中，以监测双螺旋DNA，适体和DNA酶等不同系统中核苷酸链的构象变化。最后，我们讨论了探测单分子结构转变的未来挑战，并为该领域的进一步突破提供了前景。

更新日期：2020-10-22

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11