Magnetotactic bacteria have the unique ability to synthesize magnetosomes (nano-sized magnetite or greigite crystals arranged in chain-like structures) in a variety of shapes and sizes. The chain alignment of magnetosomes enables magnetotactic bacteria to sense and orient themselves along geomagnetic fields. There is steadily increasing demand for magnetosomes in the areas of biotechnology, biomedicine, and environmental protection. Practical difficulties in cultivating magnetotactic bacteria and achieving consistent, high-yield magnetosome production under artificial environmental conditions have presented an obstacle to successful development of magnetosome applications in commercial areas. Here, we review information on magnetosome biosynthesis and strategies for enhancement of bacterial cell growth and magnetosome formation, and implications for improvement of magnetosome yield on a laboratory scale and mass-production (commercial or industrial) scale.

中文翻译：

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磁小体大规模生产的改进方法及其应用：综述


趋磁细菌具有合成各种形状和尺寸的磁小体（排列成链状结构的纳米大小的磁铁矿或镁灰石晶体）的独特能力。磁小体的链排列使趋磁细菌能够沿着地磁场感知和定向。生物技术、生物医学和环境保护领域对磁小体的需求稳步增长。在人工环境条件下培养趋磁细菌和实现一致、高产的磁小体生产的实际困难已经成为磁小体在商业领域应用成功发展的障碍。在这里，我们回顾了有关磁小体生物合成和增强细菌细胞生长和磁小体形成的策略的信息，以及对实验室规模和大规模生产（商业或工业）规模磁小体产量提高的影响。