当前位置: X-MOL 学术bioRxiv. Pharmacol. Toxicol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
EVALUATION OF ANTI-BACTERIAL AND ANTHELMINTIC ACTIVITIES OF BARK OF PLANT CASSIA FISTULA Linn.
bioRxiv - Pharmacology and Toxicology Pub Date : 2020-10-19 , DOI: 10.1101/2020.10.19.345520
Anant Nayabaniya , Samyam Aryal , Bibek Dahal , Hemanta Khanal , Anil K. Gupta

This study deals with phytochemical screening and evaluation of anti-bacterial and anthelmintic activities of the bark extracts of Cassia fistula L. The extraction with different solvents - methanol, acetone, distilled water - had been carried out. The anti-bacterial assay was done against two gram +ve and two gram -ve bacteria by agar cup diffusion method. The anthelmintic activity was done on Pheretima posthuma (earthworm) by recording the paralyzing and death time under different concentrations. Methanolic extract showed the maximum activity on both fronts be it anti-bacterial or anthelmintic. The extract was effective only against gram +ve bacteria. Among Staphylococcus aureus and Streptococci faecalis, the former was more susceptible. The activity against gram -ve bacteria was not found. In case of anthelmintic activity, the concentration of 50 mg/ml was effective and near to the paralyzing and death time as recorded for the 10 mg/ml concentration of the standard Albendazole. However, aqueous extract was more effective than the acetone extract.

中文翻译:

植物瘘管树皮皮的抗细菌和驱虫活性的评价。

这项研究涉及决明子树皮提取物的植物化学筛选和抗菌和驱虫活性的评估。已经进行了用不同溶剂(甲醇,丙酮,蒸馏水)的提取。通过琼脂杯扩散法对两克+ ve和两克-ve细菌进行了抗菌测定。通过记录在不同浓度下的瘫痪和死亡时间,对狐蝠(Pheretima posthuma)进行驱虫活性。甲醇提取物在抗菌或驱虫方面均表现出最大的活性。提取物仅对革兰氏阳性细菌有效。在金黄色葡萄球菌和粪链球菌中,前者更易感。没有发现抗革兰氏阴性菌的活性。如果发生驱虫活动,50 mg / ml的浓度是有效的,并且接近10 mg / ml的标准阿苯达唑浓度所记录的瘫痪和死亡时间。然而,水提取物比丙酮提取物更有效。
更新日期:2020-10-20
down
wechat
bug