The immune system and the nervous system are complex, but their crucial roles in many aspects of normal physiology and in disease pathogenesis mean that each has been extensively studied and characterized. The rather fixed architecture of the nervous system contrasts to the roaming, flexible nature of the immune system, but both make specific responses to various stimuli and feature, in different ways, a capacity for memory. Notably, studies in the past decade have discovered extensive bidirectional interactions between the two systems that operate in a wide range of responses in health and disease, offering a hope of novel therapeutic approaches for immunological and neurological disorders. This Special Issue, which includes four review articles and one research article, demonstrates several aspects of how the two systems are inter-connected.

中文翻译：

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简介：免疫神经连接特刊

免疫系统和神经系统很复杂，但是它们在正常生理学和疾病发病机理的许多方面都起着至关重要的作用，这意味着它们已经得到了广泛的研究和表征。神经系统的固定结构与免疫系统漫游，灵活的特性形成鲜明对比，但是它们都以各种方式对各种刺激和特征做出特定的反应，以不同的方式记忆。值得注意的是，过去十年中的研究发现，在健康和疾病中有广泛反应的两个系统之间存在广泛的双向相互作用，这为免疫和神经疾病的新型治疗方法提供了希望。本期特刊包含四篇评论文章和一篇研究文章，展示了两个系统如何相互连接的几个方面。