This study aimed to compare the long-term weight loss results, remission of comorbidities and nutritional deficiencies of sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB) and One-Anastomosis gastric bypass (OAGB) on type 2 diabetic (T2D) patients. Patients and Methods: A retrospective analysis of all the morbidly obese and diabetic patients undergoing SG, RYGB, and OAGB as primary bariatric procedures between February 2010 and June 2015 was performed. Anthropometric parameters, remission of comorbidities, nutritional deficiencies and supplementation requirements at 1, 2 and 5 years’ follow-up were monitored. Patients lost to follow-up 5 years after surgery were excluded from the analysis. Results: 358 patients were included. The follow-up rate was 84.8%. Finally, 83 SG, 152 RYGB, and 123 OAGB patients were included in the analysis. OAGB obtained significantly greater weight loss and remission of dyslipidemia than the other techniques. There was a trend towards greater T2D and hypertension remission rate after OAGB, while fasting glucose and glycated hemoglobin levels were significantly lower after OAGB. There were no significant differences in hemoglobin or protein levels between groups. SG obtained lower iron deficiencies than the other techniques, while there were no significant differences in other nutritional deficiencies between groups. Conclusion: OAGB obtained greater weight loss and remission of dyslipidemia than RYGB or SG. Excluding lower iron deficiency rates after SG, there were no significant differences in the development of nutritional deficiencies between groups.

中文翻译：

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2型糖尿病（T2D）患者的长期体重减轻结果，袖套胃切除术（SG），Roux-En-Y胃旁路术（RYGB）和一解剖胃旁路术（OAGB）的合并症和营养缺乏症

这项研究旨在比较2型糖尿病（SG），Roux-en-Y胃旁路（RYGB）和单吻合胃旁路（OAGB）的长期减肥结果，合并症和营养缺乏症的缓解T2D）患者。患者和方法：对2010年2月至2015年6月期间接受SG，RYGB和OAGB作为主要减肥手术的所有病态肥胖和糖尿病患者进行回顾性分析。监测1、2和5年随访的人体测量学参数，合并症的缓解，营养不足和补充要求。手术后5年失去随访的患者被排除在分析之外。结果：包括358例患者。随访率为84.8％。最后，分析中包括83 SG，152 RYGB和123 OAGB患者。与其他技术相比，OAGB的减肥和血脂异常的缓解明显更大。OAGB后有更高的T2D和高血压缓解率的趋势，而OAGB后空腹血糖和糖化血红蛋白水平显着降低。两组之间的血红蛋白或蛋白质水平无显着差异。SG的铁缺乏症低于其他技术，而各组之间其他营养缺乏症之间也没有显着差异。结论：与RYGB或SG相比，OAGB的减肥和血脂异常减轻更大。除SG后较低的铁缺乏率外，各组之间营养缺乏的发生没有显着差异。OAGB后有更高的T2D和高血压缓解率的趋势，而OAGB后空腹血糖和糖化血红蛋白水平显着降低。两组之间的血红蛋白或蛋白质水平无显着差异。SG的铁缺乏症低于其他技术，而各组之间其他营养缺乏症之间也没有显着差异。结论：与RYGB或SG相比，OAGB的减肥和血脂异常减轻更大。除SG后较低的铁缺乏率外，各组之间营养缺乏的发生没有显着差异。OAGB后有更高的T2D和高血压缓解率的趋势，而OAGB后空腹血糖和糖化血红蛋白水平显着降低。两组之间的血红蛋白或蛋白质水平无显着差异。SG的铁缺乏症低于其他技术，而各组之间其他营养缺乏症之间也没有显着差异。结论：与RYGB或SG相比，OAGB的减肥和血脂异常减轻更大。除SG后较低的铁缺乏率外，各组之间营养缺乏的发生没有显着差异。两组之间的血红蛋白或蛋白质水平无显着差异。SG的铁缺乏症低于其他技术，而各组之间其他营养缺乏症之间也没有显着差异。结论：与RYGB或SG相比，OAGB的减肥和血脂异常减轻更大。除SG后较低的铁缺乏率外，各组之间营养缺乏的发生没有显着差异。两组之间的血红蛋白或蛋白质水平无显着差异。SG的铁缺乏症低于其他技术，而各组之间其他营养缺乏症之间也没有显着差异。结论：与RYGB或SG相比，OAGB的减肥和血脂异常减轻更大。除SG后较低的铁缺乏率外，各组之间营养缺乏的发生没有显着差异。