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Perspectives on Human Hearing Loss, Cochlear Regeneration, and the Potential for Hearing Restoration Therapies
Brain Sciences ( IF 2.7 ) Pub Date : 2020-10-20 , DOI: 10.3390/brainsci10100756
Patricia M White 1
Affiliation  

Most adults who acquire hearing loss find it to be a disability that is poorly corrected by current prosthetics. This gap drives current research in cochlear mechanosensory hair cell regeneration and in hearing restoration. Birds and fish can spontaneously regenerate lost hair cells through a process that has become better defined in the last few years. Findings from these studies have informed new research on hair cell regeneration in the mammalian cochlea. Hair cell regeneration is one part of the greater problem of hearing restoration, as hearing loss can stem from a myriad of causes. This review discusses these issues and recent findings, and places them in the greater social context of need and community.

中文翻译:


关于人类听力损失、耳蜗再生和听力恢复治疗潜力的观点



大多数患有听力损失的成年人发现这是一种目前的假肢很难矫正的残疾。这一差距推动了当前耳蜗机械感觉毛细胞再生和听力恢复的研究。鸟类和鱼类可以通过过去几年得到更好定义的过程自发再生丢失的毛细胞。这些研究的结果为哺乳动物耳蜗毛细胞再生的新研究提供了信息。毛细胞再生是听力恢复这一更大问题的一部分,因为听力损失可能由多种原因引起。本综述讨论了这些问题和最近的发现,并将它们置于需求和社区的更大社会背景中。
更新日期:2020-10-20
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