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Effectiveness of sorting tests for detecting cognitive decline in older adults with dementia and other common neurodegenerative disorders: a meta-analysis
Neuroscience & Biobehavioral Reviews ( IF 7.5 ) Pub Date : 2020-10-20 , DOI: 10.1016/j.neubiorev.2020.10.013
A M Foran 1 , J L Mathias 1 , S C Bowden 2
Affiliation  

The demand for simple, accurate and time-efficient screens to detect cognitive decline at point-of-care is increasing. Sorting tests are often used to detect the ‘executive’ deficits that are commonly associated with behavioural-variant frontotemporal dementia (bvFTD), but their potential for use as a cognitive screen with older adults is unclear. A comprehensive search of four databases identified 142 studies that compared the sorting test performance (e.g. WCST, DKEFS-ST) of adults with a common neurodegenerative disorder (e.g. Alzheimer’s disease, vascular dementia, bvFTD, Parkinson’s disease) and cognitively-healthy controls. Hedges’ g effect sizes were used to compare the groups on five common test scores (Category, Total, Perseveration, Error, Description). The neurodegenerative disorders (combined) showed large deficits on all scores (g -1.0 to -1.3), with dementia (combined subtypes) performing more poorly (g -1.2 to -2.1), although bvFTD was not disproportionately worse than the other dementias. Overall, sorting tests detected the cognitive impairments caused by common neurodegenerative disorders, especially dementia, highlighting their potential suitability as a cognitive screen for older adults.



中文翻译:

排序测试对老年痴呆症和其他常见神经退行性疾病的认知能力下降的有效性:一项荟萃分析

对于简单,准确和省时的屏幕以检测即时诊断能力下降的需求正在增加。排序测试通常用于检测通常与行为变异性额颞痴呆(bvFTD)相关的“执行性”缺陷,但尚不清楚它们是否可用于老年人的认知筛查。对四个数据库的全面搜索确定了142项研究,这些研究比较了具有常见神经退行性疾病(例如阿尔茨海默氏病,血管性痴呆,bvFTD,帕金森氏病)和认知健康对照的成年人的分类测试表现(例如WCST,DKEFS-ST)。套期效果大小用于比较五个常见测试分数(类别,总计,坚持,错误,描述)上的组。神经退行性疾病(合并)在所有评分(g -1.0至-1.3)上均表现出较大的缺陷,痴呆(合并亚型)的表现较差(g -1.2至-2.1),尽管bvFTD并没有比其他痴呆症严重得多。总体而言,分类测试检测到由常见的神经退行性疾病(尤其是痴呆症)引起的认知障碍,突显了它们作为老年人认知筛查的潜在适用性。

更新日期:2020-10-29
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